cmRNAbone Consortium's Activities at EORS 2023 in Porto, Portugal

The 31st Annual Meeting of the European Orthopaedic Research Society (EORS) took place from September 27th to 29th 2023 in Porto, Portugal. cmRNAbone consortium partners actively participated in the event, spreading the word about project results and receiving significant recognition, including a notable achievement. Below, you'll discover details and proof of our diverse contributions to EORS 2023.

#1 Keynote by Project Coordinator Prof Martin Stoddart
cmRNAbone coordinator Prof Martin Stoddart gave an invited Keynote presentation discussing how mechanics can direct stem cell fate and tissue formation. Mechanics are key in directing the outcome for bone and cartilage injuries and using Bioreactor systems, Prof Stoddart and his team have identified some key early triggers of stem cell differentiation.

#2 cmRNAbone Partners Symposium
Elizabeth Balmayor and Martijn van Griensven organised a symposium on the role of the immune system, blood vessels, and nerves in bone regeneration. This is part of the research done by the cmRNAbone consortium, where partners investigate the role of different cmRNA molecules in stimulating osteogenesis, angiogenesis, and innervation during osteoporotic bone healing. Martijn van Griensven delivered a keynote talk on the immune system and osteogenesis, while consortium partner Andrea Banfi talked about angiogenesis and its relevant role in bone homeostasis and healing.


#3 ON Foundation Symposium
cmRNAbone partner Elizabeth Balmayor participated as an invited speaker in the ON Foundation’s organized symposium “Most promising strategies for the regeneration of your joints: make your own choice”. The symposium highlighted three emerging technologies in the field of regenerative medicine – mRNA, extracellular vesicles, and expanded cells on biomaterials and selected the most promising one based on audience voting. Elizabeth Balmayor pitched for mRNA technologies and presented the work performed by cmRNAbone, which won the most promising, translatable technology among the presented ones.


Audience votes before the keynote speakers pitched each technology:


Audience votes after the keynote speakers pitched each technology:


#4 cmRNAbone’s Industrial Partner Presentation
On Wednesday, 27th September, cmRNAbone partner Nathan Kucko from Kuros Biosciences gave a presentation titled "Results of Biphasic Calcium Phosphate Bone Graft with Submicron-Sized Needle-Shaped Surface Topography as Standard of Care Favourable in a Prospective, Multicenter, Randomized, Intra-patient Controlled Trial". Moreover, Nathan gave a Keynote lecture titled "Evaluation of a Calcium Phosphate-collagen Matrix Bone Graft with Needle-shaped Submicron Surface Topography in a Clinically Relevant Sheep Posterior Lumbar Spine Fusion Model" on the following day.


#5 cmRNAbone’s PhD Student Presentation
cmRNAbone’s PhD student Claudia Del Toro Runzer from the department cBITE of the MERLN Institute at Maastricht University presented her results on the frame of the cmRNAbone project.